A 5-year study of the bacterial pathogens associated with acute diarrhoea on the island of Crete, Greece, and their resistance to antibiotics

Eur J Epidemiol. 2003;18(1):85-90. doi: 10.1023/a:1022528205793.

Abstract

During a 5-year period (1995-1999) a total of 7090 stool samples obtained from patients with acute diarrhoea, mostly community-acquired, were examined for bacterial pathogens, in the Greek island of Crete. One or more enteric pathogens were isolated from 987 patients (14%). Salmonella enterica were the most commonly isolated bacteria (6%), followed by Campylobacter spp. (4.2%), and enteropathogenic Escherichia coli (EPEC) (1.8%). Yersinia enterocolitica (0.6%), Shigella spp. (0.3%), and Aeromonas hydrophila (0.04%), were less frequently isolated. Clostridium difficile was isolated from 65 out of 451 diarrhoeal specimens examined (14.4%). Toxin B was detected in all cases. No verotoxigenic E. coli strains were identified. Resistance to ampicillin was observed in 31.5% of the Salmonella, 58.3% of the Shigella and 31.5% of the EPEC isolates. Resistance to trimethoprim-sulfamethoxazole was observed in 4.4% of the Salmonella, 30.5% of the Shigella, and 18.5% of the EPEC isolates. High percentages of resistance to quinolones (44.5% to norfloxacin, and 40.5% to ciprofloxacin), were found among Campylobacter isolates, while resistance to erythromycin was observed in 14.9% of them. With the present study we continue the surveillance of bacterial pathogens associated with diarrhoeal disease on the island of Crete.

MeSH terms

  • Acute Disease
  • Adolescent
  • Aeromonas hydrophila / drug effects
  • Aeromonas hydrophila / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Infections / drug therapy
  • Bacterial Infections / epidemiology*
  • Bacterial Infections / microbiology
  • Campylobacter coli / drug effects
  • Campylobacter coli / isolation & purification
  • Child
  • Child, Preschool
  • Clostridioides difficile / drug effects
  • Clostridioides difficile / isolation & purification
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / microbiology
  • Cross Infection / drug therapy
  • Cross Infection / microbiology
  • Diarrhea / drug therapy*
  • Diarrhea / microbiology*
  • Drug Resistance, Bacterial*
  • Enterobacteriaceae / classification
  • Enterobacteriaceae / drug effects*
  • Enterobacteriaceae / isolation & purification*
  • Female
  • Greece / epidemiology
  • Humans
  • Infant
  • Male
  • Prevalence
  • Travel

Substances

  • Anti-Bacterial Agents