Asymmetric synthesis of all stereoisomers of 6-methylpipecolic acids

H Takahata; M Shimizu

doi:10.1007/s00726-002-0411-8

Asymmetric synthesis of all stereoisomers of 6-methylpipecolic acids

Amino Acids. 2003 Apr;24(3):267-72. doi: 10.1007/s00726-002-0411-8.

Authors

H Takahata¹, M Shimizu

Affiliation

¹ Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, Sendai 981-8558, Japan. takahata@tohoku-pharm.ac.jp

PMID: 12707808
DOI: 10.1007/s00726-002-0411-8

Abstract

Asymmetric synthesis of all four stereoisomers of 6-methylpipecolic acids with high enantiomeric purity via iterative AD reaction, starting from 1,6-heptadiene, has been described.

MeSH terms

Alkadienes / chemical synthesis
Alkadienes / chemistry
Models, Chemical
Molecular Structure
Pipecolic Acids / chemical synthesis*
Pipecolic Acids / chemistry
Stereoisomerism

Substances

Alkadienes
Pipecolic Acids