Candidemia in a tertiary care hospital: epidemiology and factors influencing mortality

Eur J Clin Microbiol Infect Dis. 2003 Apr;22(4):254-7. doi: 10.1007/s10096-003-0890-x. Epub 2003 Mar 22.


The present study was conducted in order to assess the epidemiology and clinical course of candidemia and to identify the risk factors associated with mortality. A total of 143 episodes of nosocomial candidemia were identified during a 5-year period, and these were included in the study. The majority of candidemic episodes were due to Candida albicans (63, 44%), followed by Candida parapsilosis(32, 22%). The overall mortality was 45%. The following independent prognostic factors for mortality were identified: bacterial sepsis, rapidly fatal illness, chronic obstructive lung disease, presence of a central venous catheter, candidemia due to Candida albicans, and lack of antifungal therapy.

MeSH terms

  • Adult
  • Aged
  • Candida / classification*
  • Candida / isolation & purification
  • Candida albicans / classification
  • Candida albicans / isolation & purification
  • Candidiasis / epidemiology*
  • Candidiasis / microbiology
  • Candidiasis / mortality
  • Female
  • Fungemia / epidemiology*
  • Fungemia / microbiology
  • Fungemia / mortality
  • Hospitals, Teaching*
  • Humans
  • Male
  • Middle Aged
  • Risk Factors