Expression zones of three novel genes abut the developing anterior neural plate of Xenopus embryo

Gene Expr Patterns. 2003 May;3(2):225-30. doi: 10.1016/s1567-133x(02)00077-7.


We identified three novel genes that were expressed within the anterior non-neural ectoderm of Xenopus early neurula embryos. The expression of these genes was observed in the different areas complementary to the expression zone of a homeodomain gene Xanf-1 in the anterior neural plate. One of these genes, a Ras-like GTP-ase Ras-dva, marked the anterior placodal ectoderm area; a second, an Agr family homologous gene, XAgr2, was expressed in the anterior-most ectoderm in the cement gland primordium, and a third, novel gene Nlo was expressed in the lateral neural folds. The genes were transiently expressed in the developing cement and hatching gland primordia, and repressed in the mature cement and hatching glands. XAgr2 and Nlo were also expressed in the otic vesicles, and Ras-dva was expressed in the dorso-lateral column of the neural tube.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Central Nervous System / embryology*
  • Central Nervous System / metabolism
  • Embryo, Nonmammalian / metabolism*
  • Gene Expression Profiling
  • Homeodomain Proteins / metabolism
  • Molecular Sequence Data
  • Organ Specificity
  • Sequence Alignment
  • Xenopus
  • Xenopus Proteins*


  • HESX1 protein, Xenopus
  • Homeodomain Proteins
  • Xenopus Proteins

Associated data

  • GENBANK/AF314056
  • GENBANK/AF513854
  • GENBANK/AY177202