Guillain-Barré syndrome associated with immune reconstitution

Clin Infect Dis. 2003 May 1;36(9):e111-4. doi: 10.1086/368311. Epub 2003 Apr 14.


We report a case of acute Guillain-Barré syndrome (GBS) associated with a prompt and vigorous immune reconstitution and decrease in the virus load noted during treatment with a potent regimen of highly active antiretroviral therapy. We hypothesize that GBS may have been due to an aberrant immune response or an adverse drug reaction in association with preexisting peripheral neurologic disease.

Publication types

  • Case Reports

MeSH terms

  • Anti-HIV Agents / therapeutic use
  • Antiretroviral Therapy, Highly Active / adverse effects*
  • Guillain-Barre Syndrome / etiology
  • Guillain-Barre Syndrome / immunology*
  • HIV Infections / drug therapy
  • Humans
  • Immunity / drug effects
  • Male
  • Middle Aged


  • Anti-HIV Agents