R/qtl: QTL mapping in experimental crosses

Bioinformatics. 2003 May 1;19(7):889-90. doi: 10.1093/bioinformatics/btg112.


Summary: R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates.

Availability: The package is freely available at http://www.biostat.jhsph.edu/~kbroman/qtl.

Publication types

  • Evaluation Study

MeSH terms

  • Algorithms*
  • Chromosome Mapping / methods*
  • Chromosomes, Human, Pair 1 / genetics
  • Crosses, Genetic*
  • Gene Expression Profiling / methods*
  • Genetic Markers
  • Genome
  • Genotype*
  • Humans
  • Inbreeding
  • Markov Chains
  • Models, Genetic
  • Models, Statistical
  • Quantitative Trait Loci / genetics*
  • Software*


  • Genetic Markers