Protein microarrays: meeting analytical challenges for clinical applications

Cancer Cell. 2003 Apr;3(4):317-25. doi: 10.1016/s1535-6108(03)00086-2.


Protein microarrays, one emerging class of proteomic technologies, have broad applications for discovery and quantitative analysis. A rapidly expanding use of this technology is the acquisition of information about the posttranslational modifications of proteins reflecting the activity state of signal pathways and networks, and is now employed for the analysis of biopsy samples in clinical trial research.

Publication types

  • Review

MeSH terms

  • Animals
  • Antibodies
  • Biotechnology
  • Humans
  • Neoplasms / genetics*
  • Neoplasms / therapy
  • Protein Array Analysis / methods*
  • Proteome
  • Sensitivity and Specificity
  • Signal Transduction*


  • Antibodies
  • Proteome