Sleuthing molecular targets for neurological diseases at the neuromuscular junction

Nat Rev Neurosci. 2003 May;4(5):339-52. doi: 10.1038/nrn1101.

Authors

Andrew G Engel¹, Kinji Ohno, Steven M Sine

Affiliation

¹ Department of Neurology and Neuromuscular Research Laboratory, Mayo Clinic, Rochester, Minnesota 55905, USA. age@mayo.edu

PMID: 12728262
DOI: 10.1038/nrn1101

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Acetylcholinesterase / genetics
Acetylcholinesterase / metabolism
Animals
Choline O-Acetyltransferase / genetics
Choline O-Acetyltransferase / metabolism
Electrophysiology
Humans
Muscle Proteins / genetics
Muscle Proteins / metabolism
Mutation
Myasthenic Syndromes, Congenital / genetics
Myasthenic Syndromes, Congenital / metabolism*
Neuromuscular Junction / physiology*
Protein Conformation
Receptors, Cholinergic / chemistry
Receptors, Cholinergic / genetics
Receptors, Cholinergic / metabolism
Synaptic Transmission / physiology

Substances

Muscle Proteins
Receptors, Cholinergic
peripheral membrane protein 43K
Choline O-Acetyltransferase
Acetylcholinesterase