Bacterial endocarditis complicating pregnancy: case report and systematic review of the literature

Arch Gynecol Obstet. 2003 Oct;268(4):251-5. doi: 10.1007/s00404-003-0485-x. Epub 2003 May 1.


Introduction: Infectious endocarditis is a rare life-threatening complication of pregnancy. We report a pregnancy complicated by a 3.5-cm infected vegetation of the tricuspid valve initially presenting as unilateral hip pain as well as systematic review of this entity.

Sources: A MEDLINE review of the English language literature from 1965 to present using the search terms 'endocarditis', 'pregnancy' and 'infection' as well as review of references was performed.

Results: Sixty-eight cases of infectious endocarditis complicating pregnancy were identified. The calculated maternal and fetal mortality rates were 22.1% and 14.7% respectively.

Conclusions: With persistent symptomatic lesions, delivery should be considered without regard to measures of fetal lung maturity because of high fetal mortality rates.

Publication types

  • Case Reports
  • Review
  • Systematic Review

MeSH terms

  • Adult
  • Bacteremia
  • Cesarean Section
  • Chest Pain
  • Endocarditis, Bacterial / diagnosis*
  • Endocarditis, Bacterial / epidemiology
  • Endocarditis, Bacterial / microbiology
  • Female
  • Fetal Death
  • Gestational Age
  • Heart Septal Defects, Ventricular / complications
  • Heart Septal Defects, Ventricular / surgery
  • Humans
  • Male
  • Maternal Mortality
  • Oxygen / blood
  • Pregnancy
  • Pregnancy Complications, Infectious / microbiology*
  • Streptococcal Infections
  • Tachycardia
  • Tricuspid Valve / microbiology
  • Viridans Streptococci / isolation & purification


  • Oxygen