Treatment responsiveness of the Self-Esteem And Relationship questionnaire in erectile dysfunction

Urology. 2003 May;61(5):888-92. doi: 10.1016/s0090-4295(03)00041-4.


Objectives: To determine the treatment responsiveness of the disease-specific Self-Esteem And Relationship (SEAR) questionnaire in erectile dysfunction.

Methods: The SEAR questionnaire was administered at baseline and at the end of the study in 93 patients with erectile dysfunction enrolled in a 10-week, open-label, flexible-dose (50-mg sildenafil, adjustable to 25 mg or 100 mg) trial. Changes from the baseline score were analyzed using the paired t test. The correlation between the changes from baseline on the SEAR questionnaire and the Erectile Function domain of the International Index of Erectile Function was examined.

Results: Significant and meaningful differences (P = 0.0001) from baseline were observed in the two primary domains (Sexual Relationship and Confidence) and the two Confidence domain subscales (Self-Esteem and Overall Relationship). The magnitude of the change was quite high for most aspects (Sexual Relationship, effect size [ES] = 1.6; Confidence, ES = 1.0; Self-Esteem, ES = 1.1) and moderate for one (Overall Relationship, ES = 0.6). Changes in Erectile Function domain score correlated moderately with changes in the SEAR domain and subscale scores (Sexual Relationship, r = 0.69; Confidence, r = 0.48; Self-Esteem, r = 0.47; and Overall Relationship, r = 0.35; P <or=0.001).

Conclusions: The SEAR questionnaire is responsive to effective treatment of erectile dysfunction. These data suggest that the SEAR questionnaire is a valid instrument for detecting psychosocial gains from beneficial intervention.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adult
  • Aged
  • Comorbidity / trends
  • Drug Administration Schedule
  • Erectile Dysfunction / epidemiology
  • Erectile Dysfunction / psychology*
  • Erectile Dysfunction / therapy*
  • Humans
  • Male
  • Middle Aged
  • Piperazines / administration & dosage
  • Piperazines / therapeutic use
  • Purines
  • Quality of Life
  • Self Concept*
  • Sildenafil Citrate
  • Sulfones
  • Surveys and Questionnaires*
  • Vasodilator Agents / administration & dosage
  • Vasodilator Agents / therapeutic use


  • Piperazines
  • Purines
  • Sulfones
  • Vasodilator Agents
  • Sildenafil Citrate