MRI of intracerebral hematoma: value of vasogenic edema ratio for predicting the cause

Neuroradiology. 2003 Jun;45(6):357-62. doi: 10.1007/s00234-003-0994-0. Epub 2003 May 8.

Abstract

We evaluated a method for quantifying vasogenic edema (VE) on MRI to identify brain hematomas caused by neoplasms. We performed a blinded review of 68 acute and subacute hematomas caused by neoplasms (22), hypertension or presumed amyloid angiopathy (27), or vascular malformations (19). The extent of vasogenic edema was quantified on an axial T2-weighted image using the VE ratio: the maximum width of high signal surrounding a hematoma and the mean diameter of the hematoma. Hematomas caused by neoplasm were associated with more vasogenic edema (mean VE ratio 104%+/-15%; mean VE width 2.4+/-0.7 cm) than non-neoplastic hematomas (mean VE ratio 37%+/-5%; P =0.001). When the width of VE was equal to or more half the diameter the hematoma (VE ratio 50%), the positive predictive value for tumor was 66%; when it was equal to or more than the diameter, the positive predictive value was 71%. All six hematomas with VE ratios > or = 150% were caused by neoplasm.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Astrocytoma / diagnosis
  • Astrocytoma / pathology
  • Biopsy
  • Brain Edema / diagnosis
  • Brain Edema / etiology
  • Brain Edema / pathology
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / pathology
  • Cerebral Angiography
  • Cerebral Hemorrhage / classification
  • Cerebral Hemorrhage / diagnosis*
  • Cerebral Hemorrhage / etiology
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Hematoma / diagnosis*
  • Hematoma / etiology
  • Humans
  • Infant
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Statistics as Topic
  • Tomography, X-Ray Computed