Two Cases of Cerebral Aspergillosis Successfully Treated With Voriconazole

Eur J Clin Microbiol Infect Dis. 2003 May;22(5):297-9. doi: 10.1007/s10096-003-0934-2. Epub 2003 May 10.

Abstract

Described here are two cases of cerebral aspergillosis successfully treated with voriconazole after the failure of first-line treatment with amphotericin B deoxycholate. In both cases, clinical and radiological cure was achieved within 6 weeks. Voriconazole should be considered as first-line therapy for cerebral aspergillosis.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Antifungal Agents / administration & dosage*
  • Brain Diseases / diagnosis
  • Brain Diseases / drug therapy*
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Infusions, Intravenous
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neuroaspergillosis / diagnosis
  • Neuroaspergillosis / drug therapy*
  • Pyrimidines / administration & dosage*
  • Treatment Outcome
  • Triazoles / administration & dosage*
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Voriconazole