Bioresorbable polymeric stents: current status and future promise

J Biomater Sci Polym Ed. 2003;14(4):299-312. doi: 10.1163/156856203321478838.

Abstract

Metal stents and, more recently, polymer-coated metal stents are used to stabilize dissections, eliminate vessel recoil, and guide remodeling after balloon angioplasty and other treatments for arterial disease. Bioresorbable polymeric stents are being developed to improve the biocompatibility and the drug reservoir capacity of metal stents, and to offer a transient alternative to the permanent metallic stent implant. Following a brief review of metal stent technology, the emerging class of expandable, bioresorbable polymeric stents is described, with emphasis on developments in the authors' laboratory.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Biodegradation, Environmental
  • Coated Materials, Biocompatible
  • Drug Delivery Systems
  • Humans
  • Polymers*
  • Prosthesis Implantation
  • Stents / trends*

Substances

  • Coated Materials, Biocompatible
  • Polymers