An integrative medicine approach to premenstrual syndrome

Am J Obstet Gynecol. 2003 May;188(5 Suppl):S56-65. doi: 10.1067/mob.2003.403.


Complementary and alternative medicine (CAM) approaches are widely used by women with premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). This article provides a comprehensive review of the medical literature on clinical applications of CAM for these conditions. The information was collected via a Medline review dating back to 1966 and subsequent selected review of bibliographies from these articles for non-Medline referenced but relevant clinical studies. For many of the therapies discussed, there is a lack of conclusive evidence either confirming or refuting efficacy. For other therapies, including certain herbal and nutritional approaches, the use of exercise, and the use of mind-body approaches, there is substantial evidence of efficacy. This review will be relevant to the practicing clinician seeking to become aware of and to understand the relevance of the complementary/alternative therapies being used by his/her patients for PMS and PMDD.

Publication types

  • Review

MeSH terms

  • Cimicifuga
  • Complementary Therapies*
  • Dietary Supplements
  • Female
  • Ginkgo biloba
  • Humans
  • Hypericum
  • Kava
  • Oenothera biennis
  • Phytotherapy
  • Premenstrual Syndrome / therapy*
  • Randomized Controlled Trials as Topic
  • Vitex