Contrast enhancement in Lhermitte-Duclos disease of the cerebellum: correlation of imaging with neuropathology in two cases

Neuroradiology. 2003 Jun;45(6):381-5. doi: 10.1007/s00234-003-0984-2. Epub 2003 May 16.

Abstract

Lhermitte-Duclos disease (LDD), also known as dysplastic gangliocytoma, is a rare cerebellar lesion. It has long been regarded as avascular. We report two patients with surgically proven LDD in whom contrast enhancement was observed on MRI. Neuropathological examination revealed proliferation of veins. We suggest that peripheral enhancement of LDD probably reflects vascular proliferation of the cerebellar venous draining system, and should be considered part of the imaging features of LDD.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebellar Neoplasms / diagnosis*
  • Cerebellar Neoplasms / pathology
  • Contrast Media*
  • Ganglioneuroma / diagnosis*
  • Ganglioneuroma / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Radiographic Image Enhancement*
  • Tomography, X-Ray Computed

Substances

  • Contrast Media