[Hepatic granulocytic sarcoma: an unusual presentation]

An Med Interna. 2003 Mar;20(3):141-4.
[Article in Spanish]


A case of granulocytic sarcoma (chloroma) of hepatic localization is presented. It is a extramedullary strange tumour, composed of immature precursors of myeloid cells. Clinically it can show, before, during or after a acute myeloid leukemia, chronic myeloproliferative disorders or myelodysplastic syndromes. Our patient, 81 year-old male, presented a process of important acute jaundice, with negative image technics, what indicated us the intrahepatic origin, negative tumorals markers, negative serology and hepatic biopsy (the piece of greenish coloration is described) what showed a hepatic sinusoides diffuse infiltration by indifferentiation cellularity, with study immuno-histochemical that was positive for the myeloperoxydase, giving a diagnose compatible with hepatic infiltration for acute myeloid leukemia. The patient doesn't present affectation of peripheral blood, and he died for acute hepatic and renal failure after 8 days of entrance.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Disease
  • Aged
  • Aged, 80 and over
  • Fatal Outcome
  • Humans
  • Leukemia, Myeloid / complications
  • Leukemia, Myeloid / pathology*
  • Liver Neoplasms / complications
  • Liver Neoplasms / pathology*
  • Male
  • Sarcoma, Myeloid / complications
  • Sarcoma, Myeloid / pathology*