The efficacy of ginger in prevention of post-operative nausea and vomiting after outpatient gynecological laparoscopy

J Med Assoc Thai. 2003 Mar;86(3):244-50.


Objective: To study the efficacy of ginger in prevention of nausea and vomiting after outpatient gynecological laparoscopy.

Study design: Double blind randomized controlled trial.

Setting: Department of Obstetrics and Gynecology, Thammasat Hospital, Faculty of Medicine, Thammasat University.

Material and method: From January, 2001-December, 2001, 80 patients who underwent outpatient gynecological laparoscopy were randomly allocated into group A (n = 40) and group B (n = 40). The patients in group A received 2 capsules of ginger (1 capsule contain 0.5 g of ginger powder) 1 h before the procedure while the patients in group B received the placebo. The visual analogue nausea scores (VANS) and vomiting times were evaluated at 2, 4 and 24 hours after operation.

Result: There was a significant difference in the incidence of the nausea between group A [12 (30%)] and group B [23 (57.50%)]. The VANS was lower in group A than in group B at 2 and 4 hours (p < 0.05). No difference of VANS at 24 hours was found in both groups. Incidence and frequency of vomiting in group A were lower than group B but there were not statistically different.

Conclusion: From our data, ginger is effective in prevention of nausea after outpatient gynecological laparoscopy.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Oral
  • Adult
  • Ambulatory Care
  • Analysis of Variance
  • Chi-Square Distribution
  • Double-Blind Method
  • Female
  • Genital Diseases, Female / surgery*
  • Ginger*
  • Humans
  • Laparoscopy / adverse effects*
  • Laparoscopy / methods
  • Middle Aged
  • Patient Satisfaction
  • Phytotherapy / methods*
  • Postoperative Nausea and Vomiting / prevention & control*
  • Probability
  • Reference Values
  • Thailand
  • Treatment Outcome