Inhibition of purified human kidney Na+,K+-ATPase by cyclosporine A: a possible mechanism for drug human nephrotoxicity

Ann N Y Acad Sci. 2003 Apr;986:633-5. doi: 10.1111/j.1749-6632.2003.tb07270.x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / enzymology
  • Cyclosporine / pharmacology*
  • Cyclosporine / toxicity
  • Humans
  • Kidney / drug effects
  • Kidney / pathology*
  • Kidney Cortex / enzymology
  • Kidney Medulla / enzymology
  • Rats
  • Rats, Wistar
  • Sodium-Potassium-Exchanging ATPase / antagonists & inhibitors*
  • Sodium-Potassium-Exchanging ATPase / isolation & purification

Substances

  • Cyclosporine
  • Sodium-Potassium-Exchanging ATPase