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. 2003 Jun 1;36(11):1424-32.
doi: 10.1086/375061. Epub 2003 May 22.

The Use of Economic Modeling to Determine the Hospital Costs Associated With Nosocomial Infections

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The Use of Economic Modeling to Determine the Hospital Costs Associated With Nosocomial Infections

Rebecca R Roberts et al. Clin Infect Dis. .

Abstract

Hospital-associated infection is well recognized as a patient safety concern requiring preventive interventions. However, hospitals are closely monitoring expenditures and need accurate estimates of potential cost savings from such prevention programs. We used a retrospective cohort design and economic modeling to determine the excess cost from the hospital perspective for hospital-associated infection in a random sample of adult medical patients. Study patients were classified as being not infected (n=139), having suspected infection (n=8), or having confirmed infection (n=17). Severity of illness and intensive unit care use were both independently associated with increased cost. After controlling for these confounding effects, we found an excess cost of $6767 for suspected infection and $15,275 for confirmed hospital-acquired infection. The economic model explained 56% of the total variability in cost among patients. Hospitals can use these data when evaluating potential cost savings from effective infection-control measures.

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