Pulmonary manifestations of inflammatory bowel disease

Inflamm Bowel Dis. 2003 Mar;9(2):104-15. doi: 10.1097/00054725-200303000-00004.


Extraintestinal manifestations of both Crohn's disease and ulcerative colitis (UC) have been well described, although pulmonary findings are often overlooked. We summarize the experience of more than 400 cases of pulmonary manifestations of inflammatory bowel disease (IBD). These manifestations will be categorized by disease mechanism into drug-induced disease, anatomic disease, over-lap syndromes, autoimmune disease, physiologic consequences of IBD, pulmonary function test abnormalities, and nonspecific lung disease. We intend to provide the clinician with a practical working update on the spectrum of pulmonary dysfunction associated with IBD.

Publication types

  • Review

MeSH terms

  • Biopsy, Needle
  • Colitis, Ulcerative / complications
  • Colitis, Ulcerative / pathology
  • Crohn Disease / complications
  • Crohn Disease / pathology
  • Female
  • Humans
  • Immunohistochemistry
  • Incidence
  • Inflammatory Bowel Diseases / complications*
  • Inflammatory Bowel Diseases / pathology*
  • Lung Diseases / epidemiology
  • Lung Diseases / etiology*
  • Lung Diseases / pathology*
  • Male
  • Prognosis
  • Radiography, Thoracic
  • Respiratory Function Tests
  • Risk Assessment
  • Severity of Illness Index
  • Tomography, X-Ray Computed