Recent advances in the development of phytoestrogens and derivatives: an update of the promising perspectives in the prevention of postmenopausal diseases

Y Jacquot; C Rojas; B Refouvelet; J F Robert; G Leclercq; A Xicluna

doi:10.2174/1389557033488006

Recent advances in the development of phytoestrogens and derivatives: an update of the promising perspectives in the prevention of postmenopausal diseases

Mini Rev Med Chem. 2003 Aug;3(5):387-400. doi: 10.2174/1389557033488006.

Authors

Y Jacquot¹, C Rojas, B Refouvelet, J F Robert, G Leclercq, A Xicluna

Affiliation

¹ Equipe de Chimie Thérapeutique, Faculté de Médecine et de Pharmacie, Place Saint-Jacques, 25030 Besançon, France.

PMID: 12769692
DOI: 10.2174/1389557033488006

Abstract

Phytoestrogens constitute a promising alternative in the treatment of diseases associated with menopause. Nevertheless, the lack of data concerning their pharmacology and their toxicology requires use precautions. After reminding the pharmacology of estrogen receptors, this review outlines the estrogenicity and the therapeutic potentialities of phytoestrogens according to their structure.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Humans
Isoflavones / chemistry*
Isoflavones / pharmacology
Isoflavones / therapeutic use*
Phytoestrogens
Plant Preparations / chemistry*
Plant Preparations / pharmacology
Plant Preparations / therapeutic use*
Postmenopause / drug effects
Postmenopause / physiology*
Preventive Medicine / methods*

Substances

Isoflavones
Phytoestrogens
Plant Preparations