Granulomatous pulmonary disease in a child: an unusual presentation of Crohn's disease

Pediatr Pulmonol. 2003 Jul;36(1):76-80. doi: 10.1002/ppul.10301.


Crohn's disease (CD) is a chronic inflammatory disorder of the bowel which may be associated with an extensive list of extraintestinal manifestations involving almost every organ system. The most common organs involved are the eyes, skin, joints, and liver. Symptomatic bronchopulmonary disorders have been reported only rarely in pediatric CD. We report on an 11-year-old child who had a recurrent cough and increasing dyspnea with exercise for 8 months before developing any gastrointestinal symptoms. He was demonstrated to have granulomatous inflammation of the lung, as well as of the gastrointestinal tract. Similarities between CD and sarcoidosis are discussed.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Bronchoscopy
  • Child
  • Crohn Disease / diagnostic imaging
  • Crohn Disease / pathology*
  • Diagnosis, Differential
  • Follow-Up Studies
  • Granuloma, Respiratory Tract / diagnostic imaging
  • Granuloma, Respiratory Tract / pathology*
  • Humans
  • Immunohistochemistry
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / pathology*
  • Male
  • Respiratory Function Tests
  • Risk Assessment
  • Severity of Illness Index
  • Tomography, X-Ray Computed