[Effects of fermented Cordyceps powder on pulmonary function in sensitized guinea pigs and airway inflammation in sensitized rats]

X X Lin; Q M Xie; W H Shen; Y Chen

[Effects of fermented Cordyceps powder on pulmonary function in sensitized guinea pigs and airway inflammation in sensitized rats]

Zhongguo Zhong Yao Za Zhi. 2001 Sep;26(9):622-5.

[Article in Chinese]

Authors

X X Lin¹, Q M Xie, W H Shen, Y Chen

Affiliation

¹ Zhejiang Respiratory Drugs Research Laboratory of State Drugs Administration of China, Zhejiang University College of Medicine, Hangzhou 310031, Zhejiang, China.

PMID: 12776432

Abstract

Objective: To study Cordyceps (artificial fermented Cordyceps sinensis(Berk.) Sacc) powderin the treatment of asthma in the animal models.

Method: Pulmonary function and airway inflammation in vivo were investigated.

Result: Cordyceps, 5g.kg-1(ig), significantly inhibited bronchial challenge of ovalbumin-induced change of RL and Cdyn (P < 0.05) and inhibited antigen-induced increase of eosinophils in the BALF of rats (P < 0.05).

Conclusion: The results suggested cordyceps could be applied for the prevention and cure of asthma.

MeSH terms

Airway Resistance / drug effects
Animals
Asthma / drug therapy
Asthma / physiopathology*
Cordyceps* / chemistry
Drugs, Chinese Herbal / isolation & purification
Drugs, Chinese Herbal / pharmacology*
Female
Guinea Pigs
Lepidoptera* / chemistry
Lung / physiopathology*
Lung Compliance / drug effects
Male
Phytotherapy*
Rats
Rats, Sprague-Dawley

Substances

Drugs, Chinese Herbal