Plasmablastic lymphoma presenting in a human immunodeficiency virus-negative patient: a case report

Ann Hematol. 2003 Aug;82(8):521-525. doi: 10.1007/s00277-003-0684-3. Epub 2003 May 29.

Abstract

Plasmablastic lymphoma (PBL), an aggressive non-Hodgkin's lymphoma that carries a poor prognosis, previously has been identified almost exclusively in patients infected with the human immunodeficiency virus (HIV). We present a case of a 42-year-old HIV-negative patient presenting with an isolated nasal cavity mass, the typical presentation for PBL. The patient was given systemic chemotherapy, central nervous system prophylaxis, and consolidative locoregional radiotherapy and achieved a complete clinical response. This case suggests PBL should be considered in HIV-negative patients with characteristic findings.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • HIV Seronegativity*
  • Humans
  • Lymphoma, Non-Hodgkin / diagnosis*
  • Lymphoma, Non-Hodgkin / pathology
  • Magnetic Resonance Imaging
  • Male
  • Nose Neoplasms / diagnosis*
  • Nose Neoplasms / pathology