Salt stress induces the expression of Schizosaccharomyces pombe och1+, which encodes an initiation-specific alpha-1,6-mannosyltransferase for N-linked outer chain synthesis of cell wall mannoproteins

Biosci Biotechnol Biochem. 2003 Apr;67(4):927-9. doi: 10.1271/bbb.67.927.

Abstract

The Schizosaccharomyces pombe Och1p is required for the initiation of outer chain elongation of N-linked oligosaccharides. In this report, we investigated the transcriptional control of the S. pombe och1+ gene and found that the expression of the och1+ gene was not regulated during the cell cycle, but was induced by NaCl and KCl through a transcription factor, Atf1p.

MeSH terms

  • Cell Cycle
  • Cell Wall / chemistry
  • Electrolytes / pharmacology*
  • Enzyme Induction / drug effects*
  • Mannosyltransferases / analysis
  • Mannosyltransferases / genetics*
  • Membrane Glycoproteins / biosynthesis
  • Potassium / pharmacology
  • RNA, Messenger / analysis
  • Schizosaccharomyces / enzymology*
  • Sodium / pharmacology
  • Transcription Factors / physiology
  • Transcription, Genetic / drug effects

Substances

  • Electrolytes
  • Membrane Glycoproteins
  • RNA, Messenger
  • Transcription Factors
  • mannoproteins
  • Sodium
  • Mannosyltransferases
  • alpha 1,6-mannosyltransferase
  • Potassium