Abstract
Established methods for analyzing behavioral traits in mutant lines of mice allow researchers to understand the outcomes of genetic manipulations in the nervous system. A rigorous six-tiered behavioral phenotyping strategy is described. Recommendations are offered for the design of mouse behavioral testing suites in animal housing facilities.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Behavior, Animal / physiology*
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Behavioral Sciences / instrumentation
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Behavioral Sciences / methods
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Genetics, Behavioral*
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Housing, Animal*
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Laboratory Animal Science / instrumentation
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Laboratory Animal Science / methods
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Mice
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Mice, Mutant Strains / genetics
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Mice, Mutant Strains / psychology*
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Phenotype
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Social Environment
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Veterinary Medicine / methods