The association between protein-energy malnutrition, malaria morbidity and all-cause mortality in West African children

Trop Med Int Health. 2003 Jun;8(6):507-11. doi: 10.1046/j.1365-3156.2003.01043.x.


Both malaria and protein-energy malnutrition (PEM) are highly prevalent in young children of sub-Saharan Africa, and the association between PEM and malaria continues to be discussed controversially. We analysed the association between PEM, malaria morbidity and all-cause mortality in a cohort of 709 children aged 6-30 months in a malaria holoendemic rural area of Burkina Faso. Study children were followed over the main malaria transmission period (June-December) in 1999 through longitudinal malaria surveillance complemented by three cross-sectional clinical surveys. There was no association between PEM and malaria morbidity, but malnourished children had a more than two-fold higher risk of dying than non-malnourished children.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthropometry
  • Burkina Faso / epidemiology
  • Child, Preschool
  • Endemic Diseases
  • Epidemiologic Methods
  • Female
  • Humans
  • Infant
  • Malaria, Falciparum / complications*
  • Malaria, Falciparum / epidemiology
  • Male
  • Mortality*
  • Population Surveillance
  • Protein-Energy Malnutrition / complications*
  • Protein-Energy Malnutrition / epidemiology
  • Rural Health
  • Sex Distribution