Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis

Adv Enzyme Regul. 2003;43:121-34. doi: 10.1016/s0065-2571(02)00038-9.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antioxidants / chemistry
  • Cell Nucleus / metabolism
  • DNA-Binding Proteins / metabolism
  • Gene Expression Regulation*
  • Humans
  • Mice
  • Models, Biological
  • Models, Genetic
  • NAD(P)H Dehydrogenase (Quinone) / metabolism
  • NF-E2-Related Factor 2
  • Neoplasms / metabolism*
  • Oxygen / metabolism
  • Protein Conformation
  • Protein Structure, Tertiary
  • Reactive Oxygen Species*
  • Trans-Activators / metabolism

Substances

  • Antioxidants
  • DNA-Binding Proteins
  • NF-E2-Related Factor 2
  • NFE2L2 protein, human
  • Nfe2l2 protein, mouse
  • Reactive Oxygen Species
  • Trans-Activators
  • NAD(P)H Dehydrogenase (Quinone)
  • Oxygen