Nonpharmacologic treatment of resistant hypertensives by device-guided slow breathing exercises

Am J Hypertens. 2003 Jun;16(6):484-7. doi: 10.1016/s0895-7061(03)00571-5.


Background: Recent studies have demonstrated the antihypertensive effect of slow breathing exercises, guided interactively by a device, in patients with uncontrolled blood pressure (BP) without changing medication. This study examined the response to the same treatment protocol in resistant hypertensives.

Methods: Seventeen resistant hypertensives exercised device-guided slow breathing for 8 weeks, 15 min daily, and self-monitored BP. Data stored in the devices were collected on a PC-based system. Clinical outcomes were office and home BP changes from baseline to end values.

Results: Significant reductions in both office BP (-12.9/-6.9 mm Hg, P <.001 and home BP (-6.4/-2.6 mm Hg, P <.01/P <.05) without side effects with 82% responders and good compliance.

Conclusions: Resistant hypertensives can benefit from and are compliant with self-treatment by device-guided slow breathing.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Blood Pressure
  • Breathing Exercises*
  • Equipment and Supplies
  • Female
  • Follow-Up Studies
  • Humans
  • Hypertension / therapy*
  • Male
  • Middle Aged
  • Patient Compliance