Physical, mental, and social predictors of functional outcome in unilateral lower-limb amputees

Arch Phys Med Rehabil. 2003 Jun;84(6):803-11. doi: 10.1016/s0003-9993(02)04952-3.


Objective: To study the value of physical, mental, and social characteristics as predictors of functional outcome of elderly amputees.

Design: Prospective, inception cohort study; comparisons with reference populations.

Setting: Main hospitals, rehabilitation centers, nursing homes, patients' own residence settings in 1 of the 3 northern provinces in the Netherlands.

Participants: Forty-six patients older than 60 years, with unilateral transtibial or transfemoral amputation or knee disarticulation because of vascular disease.

Interventions: Measurement of physical, mental, and social predictors 2 and 6 weeks postamputation.

Main outcome measures: The Sickness Impact Profile (SIP-68), Groningen Activity Restriction Scale (GARS), Timed up and go (TUG) test, and prosthetic use.

Results: A total of 15% of amputees died within the first year after amputation. Seventy percent lived independently at home 1 year postamputation. The functional level of the patients was low, as shown by high scores on the SIP-68 (mean, 23.6), GARS (mean, 41.2), and TUG test (mean, 23.9s). Functionally effective prosthetic use, as measured with the classification of Narang and Pohjolainen, was reached by 49%. For the SIP-68 scores, age, comorbidity, 1-leg balance, and the 15-word test predicted functional outcome in 69% of amputees. For the GARS score, age, 1-leg balance, and the 15-word test predicted functional outcome in 64%. For the TUG test, age and 1-leg balance predicted functional outcome in 42% of amputees. After correction for age, the only significant predictor for prosthetic use was 1-leg balance.

Conclusions: Elderly patients with a leg amputation had a low functional level 1-year postamputation. An important part of functional outcome could be predicted 2 weeks after amputation by age at amputation, 1-leg balance on the unaffected limb, and cognitive impairment. Severe comorbidity probably also played a role. The results may be used in the general policy concerning leg amputees.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living*
  • Aged
  • Amputation / rehabilitation*
  • Amputees / psychology*
  • Amputees / rehabilitation*
  • Artificial Limbs / statistics & numerical data
  • Female
  • Follow-Up Studies
  • Humans
  • Leg / surgery*
  • Male
  • Peripheral Vascular Diseases / surgery
  • Prospective Studies
  • Sickness Impact Profile*
  • Treatment Outcome