Expression of cVg1 mRNA During Chicken Embryonic Development

Anat Rec A Discov Mol Cell Evol Biol. 2003 Jul;273(1):603-8. doi: 10.1002/ar.a.10070.

Abstract

Using degenerated PCR-primers to identify known and novel BMPs that are expressed in the developing chicken heart, we identified not only BMP2, -4, and -7 mRNA, but also the TGFbeta superfamily member cVg1. The expression pattern of cVg1 mRNA was determined during chicken development from HH4 to HH44. In early developmental stages, cVg1 mRNA is expressed in the primitive streak, paraxial mesoderm, developing somites, and developing neural tube. Subsequently, cVg1 mRNA is expressed in the developing central and peripheral nervous system, retina, auditory vesicle, notochord, lung alveoli, and olfactory mucosa. In the heart, cVg1 is initially expressed through the linear heart tube, but becomes restricted to the forming chamber myocardium, in an expression domain similar to that of atrial natriuretic factor (ANF) mRNA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone Morphogenetic Protein 2
  • Bone Morphogenetic Protein 4
  • Bone Morphogenetic Protein 7
  • Bone Morphogenetic Proteins / genetics
  • Bone Morphogenetic Proteins / metabolism
  • Central Nervous System / embryology
  • Central Nervous System / growth & development
  • Central Nervous System / metabolism*
  • Chick Embryo / growth & development
  • Chick Embryo / metabolism*
  • Eye / embryology
  • Eye / growth & development
  • Eye / metabolism
  • Gastrula / metabolism
  • Gene Expression Profiling
  • Glycoproteins / genetics
  • Glycoproteins / metabolism*
  • Heart / embryology
  • Heart / growth & development
  • Mesoderm / metabolism
  • Myocardium / metabolism*
  • Notochord / embryology
  • Notochord / growth & development
  • Notochord / metabolism
  • Olfactory Mucosa / embryology
  • Olfactory Mucosa / growth & development
  • Olfactory Mucosa / metabolism
  • Peripheral Nervous System / embryology
  • Peripheral Nervous System / growth & development
  • Peripheral Nervous System / metabolism*
  • Pulmonary Alveoli / embryology
  • Pulmonary Alveoli / growth & development
  • Pulmonary Alveoli / metabolism
  • RNA, Messenger / analysis
  • Sense Organs / embryology
  • Sense Organs / growth & development
  • Sense Organs / metabolism*
  • Somites / metabolism
  • Transforming Growth Factor beta / metabolism

Substances

  • Bone Morphogenetic Protein 2
  • Bone Morphogenetic Protein 4
  • Bone Morphogenetic Protein 7
  • Bone Morphogenetic Proteins
  • Glycoproteins
  • RNA, Messenger
  • Transforming Growth Factor beta