Nitric oxide as a signal in blood vessels

R G Knowles; S Moncada

doi:10.1016/0968-0004(92)90008-w

Nitric oxide as a signal in blood vessels

Trends Biochem Sci. 1992 Oct;17(10):399-402. doi: 10.1016/0968-0004(92)90008-w.

Authors

R G Knowles¹, S Moncada

Affiliation

¹ Wellcome Research Laboratories, Beckenham, Kent, UK.

PMID: 1280869
DOI: 10.1016/0968-0004(92)90008-w

Abstract

In the five years since the discovery that nitric oxide is produced as a signal in blood vessels, a great deal has been discovered about the processes involved. This article reviews current knowledge about the vascular cell synthesis, effects and subsequent destruction of this messenger molecule.

Publication types

Review

MeSH terms

Amino Acid Oxidoreductases / metabolism
Animals
Blood Vessels / physiology*
Endothelium, Vascular / enzymology
Endothelium, Vascular / physiology
Humans
Nitric Oxide / metabolism*
Nitric Oxide Synthase
Signal Transduction / physiology*
Vasodilation / physiology

Substances

Nitric Oxide
Nitric Oxide Synthase
Amino Acid Oxidoreductases