Improved biotransformations on charged PEGA supports

Chem Commun (Camb). 2003 Jun 7:(11):1296-7. doi: 10.1039/b301680c.

Abstract

PEGA supports functionalised with permanent charges show superior swelling properties in aqueous media when compared to neutral PEGA; a novel positively charged PEGA resin significantly improves penicillin G amidase (PGA) catalysed biotransformation on solid support, by favouring accessibility of the negatively charged enzyme.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biotransformation
  • Polyethylene Glycols / chemistry*

Substances

  • bis(polyoxyethylene bis(amine))
  • Polyethylene Glycols