Post-traumatic inflammation following spinal cord injury

Spinal Cord. 2003 Jul;41(7):369-78. doi: 10.1038/sj.sc.3101483.

Abstract

Inflammatory reaction following a spinal cord injury (SCI) contributes substantially to secondary effects, with both beneficial and devastating effects. This review summarizes the current knowledge concerning the structural features (vascular, cellular, and biochemical events) of SCI and gives an overview of the regulation of post-traumatic inflammation.

Publication types

  • Review

MeSH terms

  • Animals
  • Calcium / metabolism
  • Cell Death
  • Free Radicals / adverse effects
  • Glial Fibrillary Acidic Protein / metabolism
  • Glutamic Acid / adverse effects
  • Humans
  • Inflammation / etiology
  • Inflammation / metabolism
  • Mitochondria / metabolism
  • Neuroglia / metabolism*
  • Neurons / metabolism*
  • Neurotoxins / adverse effects
  • Nitric Oxide / metabolism
  • Spinal Cord Injuries / metabolism*
  • Spinal Cord Injuries / pathology
  • Spinal Cord Injuries / physiopathology
  • Wallerian Degeneration / metabolism

Substances

  • Free Radicals
  • Glial Fibrillary Acidic Protein
  • Neurotoxins
  • Nitric Oxide
  • Glutamic Acid
  • Calcium