Trichinella spiralis: specificity of ES antigens from pre-encysted larvae

J Helminthol. 1992 Mar;66(1):38-44. doi: 10.1017/s0022149x00012542.


Excretory/secretory (ES) antigens were obtained by culturing pre-encysted Trichinella spiralis larvae which were recovered from muscles of experimentally infected mice 14-15 days postinfection. Analyses of these antigens (PEL ES) with immunoblotting, SDS-PAGE and Triple Antibody ELISA showed that they yielded a low sensitivity and specificity when tested with antisera against the common nematodes of Chinese pigs. As compared to ES antigens from encysted larvae, PEL ES also contained more low molecular mass proteins.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, Helminth / analysis
  • Antigens, Helminth / immunology*
  • Electrophoresis, Polyacrylamide Gel
  • Enzyme-Linked Immunosorbent Assay
  • Epitopes / analysis
  • Epitopes / immunology
  • Immune Sera / immunology
  • Immunoblotting
  • Larva / immunology
  • Swine
  • Trichinella spiralis / immunology*


  • Antigens, Helminth
  • Epitopes
  • Immune Sera