Catatonia and other psychiatric symptoms with vitamin B12 deficiency

Acta Psychiatr Scand. 2003 Aug;108(2):156-9. doi: 10.1034/j.1600-0447.2003.00089.x.


Objective: To study unusual psychiatric manifestation of vitamin B12 deficiency and related issues.

Method: A case study of 52-year-old female and review of relevant literature.

Results: Complete remission of psychiatric symptoms without recurrence for the next 4 years with vitamin B12 as the only specific therapy instituted.

Conclusion: Importance of B12 estimation and replacement in patients with varied psychiatric manifestations.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Catatonia / etiology*
  • Humans
  • Male
  • Mental Disorders / etiology*
  • Vitamin B 12 / therapeutic use
  • Vitamin B 12 Deficiency / complications*
  • Vitamin B 12 Deficiency / psychology*


  • Vitamin B 12