Discovery of a Potent Substance P Antagonist: Recognition of the Key Molecular Determinant

J Med Chem. 1992 Dec 25;35(26):4911-3. doi: 10.1021/jm00104a018.

MeSH terms

  • Humans
  • Models, Molecular
  • Receptors, Neurokinin-1
  • Receptors, Neurotransmitter / drug effects
  • Receptors, Neurotransmitter / metabolism
  • Stereoisomerism
  • Substance P / antagonists & inhibitors*

Substances

  • Receptors, Neurokinin-1
  • Receptors, Neurotransmitter
  • Substance P