The budding index of Saccharomyces cerevisiae deletion strains identifies genes important for cell cycle progression

FEMS Microbiol Lett. 2003 Jun 27;223(2):253-8. doi: 10.1016/S0378-1097(03)00384-7.


Budding marks initiation of cell division in Saccharomyces cerevisiae. Consequently, cell cycle progression can be monitored by the fraction of budded cells (budding index) in a proliferating cell population. We determined the budding index of a large collection of deletion strains, to systematically identify genes involved in cell cycle progression.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cell Cycle / genetics
  • Gene Deletion*
  • Homozygote
  • Saccharomyces cerevisiae / cytology*
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / growth & development
  • Vacuoles / physiology