Risk factors for nosocomial bloodstream infections

Br J Nurs. 2003 Jun 26-Jul 9;12(12):718, 720-6. doi: 10.12968/bjon.2003.12.12.11334.


A retrospective study of 205 patients was performed to identify the risk factors associated with nosocomial bloodstream infection (BSI). The study occurred during a 5-month period in four medical-surgical intensive care units (ICUs) in Athens, Greece. Risk factors were determined using single and multivariate analyses. Thirty-five patients developed nosocomial BSI (17.1%). The incidence density (defined as the number of new cases of BSI divided by the total of patient-days in the population studied; Jarvis, 1997) of BSI was 14.3 per 1000 patient-days (total number of days that patients are in the ICU during the selected time period). A multivariate model showed that only three factors were significantly and independently responsible for nosocomial BSI: the length of ICU stay (adjusted odds ratios (AOR) 1.052, 95% confidence interval (CI) 1.018-1.087, P = 0.002); the presence of trauma at admission (AOR 2.622, 95% CI 1.074-6.404, P = 0.034); and nosocomial ventilator-associated pneumonia (AOR 6.153, 95% CI 2.305-16.422, P = 0.000). These results show that the factors that had most influence on the development of nosocomial BSI were those factors associated with the treatment received by patients during ICU stay.

Publication types

  • Comparative Study

MeSH terms

  • Catheterization, Swan-Ganz / statistics & numerical data
  • Causality
  • Cross Infection / epidemiology*
  • Female
  • Greece / epidemiology
  • Humans
  • Incidence
  • Intensive Care Units / statistics & numerical data
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Regression Analysis
  • Respiration, Artificial / statistics & numerical data
  • Retrospective Studies
  • Risk Factors
  • Sepsis / epidemiology*
  • Tracheostomy / statistics & numerical data
  • Urinary Tract Infections / epidemiology
  • Wounds and Injuries / epidemiology