[Studies on the lignan chemical constituents from pine needles of Pinus massoniana Lamb]

Yao Xue Xue Bao. 2003 Mar;38(3):199-202.
[Article in Chinese]

Abstract

Aim: To study the chemical constituents of the pine needles from Pinus massoniana Lamb..

Methods: Various chromatographic techniques were used for the separation and purification. The physicochemical properties and spectral data were used to elucidate the structures.

Results: Three compounds were isolated from the n-BuOH fraction of water-extracts. The structures were identified as (7S,8R)-4,9'-dihydroxyl-3, 3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9-O-alpha- L-rhamnopyranoside (massonianoside D, 7), 4,4',9,9'-tetrahydroxyl-3,3'-dimethyoxyl-tetrahydrocyclolignan ((+)-isolariciresinol, 8) and 4,4',9'-trihydroxyl-3,3'-dimethyoxyl-tetrahydrocyclolignan-9-O-beta-D- xylopyranoside (isolariciresinol-9-O-xyloside, 9) on the basis of spectral data (ORD, UV, IR, MS, 1HNMR, 13CNMR, 1H-1HCOSY, HMQC and HMBC etc.).

Conclusion: Compound 7 is a new compound, while compounds 8 and 9 were isolated from this plant for the first time.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification
  • Lignans / chemistry
  • Lignans / classification
  • Lignans / isolation & purification*
  • Lignin / chemistry
  • Lignin / isolation & purification
  • Molecular Structure
  • Monosaccharides / chemistry
  • Monosaccharides / isolation & purification*
  • Naphthols / chemistry
  • Naphthols / isolation & purification
  • Pinus / chemistry*
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*

Substances

  • (7S,8R)-4,9'-dihydroxyl-3, 3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9-O-alpha- L-rhamnopyranoside
  • Drugs, Chinese Herbal
  • Lignans
  • Monosaccharides
  • Naphthols
  • isolariciresinol
  • Lignin