Fatigue and quality of life among Chinese patients with hematologic malignancy after bone marrow transplantation

Cancer Nurs. 2003 Jun;26(3):211-9; quiz 220-1. doi: 10.1097/00002820-200306000-00006.


Fatigue is reported to be a major symptom for many patients with cancer. However, little is known about this symptom among Chinese people who have cancer. A cross-sectional design was used to examine the intensity of fatigue in patients who underwent bone marrow transplantation for a hematologic malignancy, and to determine whether fatigue affected the quality of life in a Chinese sample (N = 157). The Revised Piper Fatigue Scale-Chinese Version was used to measure fatigue, and the Chinese version of the SF-36 Health Survey was used to measure quality of life. Overall, the subjects perceived a moderate level of fatigue (mean total fatigue score, 4.7 +/- 1.7). More than 15% reported experiencing a high level of fatigue. Subjects more likely to perceive a high level of fatigue were older, married, not employed, and on lower incomes. On post hoc tests, the group with a high level of fatigue scored significantly lower on quality-of-life domains than the other two groups (P <.05). The results may help nurses working with Chinese populations in identifying patients at risk for increased fatigue and in planning fatigue-relieving strategies.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bone Marrow Transplantation / adverse effects*
  • China
  • Cross-Sectional Studies
  • Disability Evaluation
  • Education, Nursing, Continuing
  • Fatigue / classification
  • Fatigue / complications*
  • Fatigue / diagnosis
  • Fatigue / physiopathology
  • Female
  • Health Surveys
  • Hematologic Neoplasms / complications*
  • Hematologic Neoplasms / surgery*
  • Humans
  • Male
  • Middle Aged
  • Quality of Life*
  • Severity of Illness Index