CDP-870. Celltech/Pfizer

Curr Opin Investig Drugs. 2003 May;4(5):588-92.

Abstract

Celltech Group plc (formerly Celltech Chiroscience), in collaboration with Pfizer Inc (formerly Pharmacia Corp), is developing CDP-870, a polyethylene glycol (PEG)ylated anti-TNF antibody fragment, for the potential treatment of certain autoimmune and inflammatory diseases, including rheumatoid arthritis (RA) and Crohn's disease (CD). In October 2002, Pharmacia initiated phase III trials for RA and at this time Celltech anticipated initiating phase III trials for CD in mid-2003.

Publication types

  • Review

MeSH terms

  • Animals
  • Antibodies, Monoclonal, Humanized
  • Autoimmune Diseases / drug therapy
  • Certolizumab Pegol
  • Clinical Trials as Topic / statistics & numerical data
  • Humans
  • Immunoglobulin Fab Fragments
  • Polyethylene Glycols / pharmacology
  • Polyethylene Glycols / therapeutic use*
  • Technology, Pharmaceutical / legislation & jurisprudence
  • Technology, Pharmaceutical / methods*

Substances

  • Antibodies, Monoclonal, Humanized
  • Immunoglobulin Fab Fragments
  • Polyethylene Glycols
  • Certolizumab Pegol