HIV vaccines 1983-2003

Nat Med. 2003 Jul;9(7):874-80. doi: 10.1038/nm0703-874.

Abstract

Twenty years after the discovery of HIV, there is still no vaccine. This year, an envelope vaccine aimed at stimulating neutralizing antibodies was unable to protect against infection in phase 3 trials. But more than 20 HIV vaccines designed to stimulate T-cell responses are being developed. Will any of them work?

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • AIDS Vaccines / immunology*
  • AIDS Vaccines / therapeutic use*
  • Antibodies / immunology
  • CD8-Positive T-Lymphocytes / immunology*
  • CD8-Positive T-Lymphocytes / virology
  • Clinical Trials as Topic
  • Drug Design
  • HIV / genetics
  • HIV / immunology
  • Humans
  • T-Lymphocytes / immunology
  • T-Lymphocytes / virology
  • Vaccines, Synthetic / immunology

Substances

  • AIDS Vaccines
  • Antibodies
  • Vaccines, Synthetic