A model-fitting implementation of the DeFries-Fulker model for selected twin data

Behav Genet. 2003 May;33(3):271-8. doi: 10.1023/a:1023494408079.


In this research note, DeFries-Fulker (DF) regression analysis is reframed in model-fitting terms, where an individual's expected score is modeled as a function of their co-twin's proband status. This more flexible implementation of the DF model allows DZ-O twins to be incorporated in a sex-limitation model. Brief simulation results are presented along with the Mx scripts used.

MeSH terms

  • Computer Simulation
  • Female
  • Humans
  • Male
  • Models, Statistical*
  • Sex Characteristics
  • Twins*
  • Twins, Dizygotic / genetics
  • Twins, Monozygotic / genetics