Infection of Acanthamoeba castellanii with Mycobacterium bovis and M. bovis BCG and survival of M. bovis within the amoebae

Stephanie J Taylor; Leena J Ahonen; Frans A A M de Leij; Jeremy W Dale

doi:10.1128/AEM.69.7.4316-4319.2003

Infection of Acanthamoeba castellanii with Mycobacterium bovis and M. bovis BCG and survival of M. bovis within the amoebae

Appl Environ Microbiol. 2003 Jul;69(7):4316-9. doi: 10.1128/AEM.69.7.4316-4319.2003.

Authors

Stephanie J Taylor¹, Leena J Ahonen, Frans A A M de Leij, Jeremy W Dale

Affiliation

¹ Microbial Sciences Group, School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom.

Abstract

Survival of Mycobacterium bovis after ingestion by protozoa would provide an environmental reservoir for infection of cattle. We have shown that M. bovis survived ingestion by Acanthamoeba castellanii. In contrast, two strains of M. bovis BCG did not survive well within Acanthamoeba.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acanthamoeba / growth & development
Acanthamoeba / microbiology*
Animals
Culture Media
Microscopy, Electron
Mycobacterium bovis / growth & development*
Mycobacterium bovis / pathogenicity*

Substances

Culture Media