Modular tubes: common principles of renal development

Curr Biol. 2003 Jul 1;13(13):R511-3. doi: 10.1016/s0960-9822(03)00442-1.


The nephrons of the vertebrate kidney originate from mesenchymal tissue that is recruited and incorporated into a branching epithelium. Key features of this unusual manner of specifying functional units within a tubular organ have now been found to be similarly employed during development of the insect renal system.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Animals
  • Drosophila / embryology*
  • Epithelium / embryology
  • Malpighian Tubules / embryology*
  • Mesoderm / physiology
  • Nephrons / embryology*
  • Organogenesis
  • Vertebrates / embryology*