The use of oxytocin in nipple fluid aspiration

Breast J. Jul-Aug 2003;9(4):266-8. doi: 10.1046/j.1524-4741.2003.09402.x.


It has been shown that early detection of breast cancer saves lives. Recently there has been increasing interest in nipple aspirate fluid as a potential avenue for breast cancer diagnosis. One major challenge regarding studies of nipple aspirate fluid is the ability to obtain adequate samples. Here we describe the use of nasal oxytocin in a group of volunteer women in order to increase the yield of nipple aspirate fluid.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Administration, Inhalation
  • Adult
  • Bodily Secretions / drug effects
  • Bodily Secretions / metabolism*
  • Breast Neoplasms / pathology*
  • Female
  • Humans
  • Inhalation
  • Nipples / drug effects
  • Nipples / metabolism*
  • Nipples / pathology*
  • Oxytocin / administration & dosage
  • Oxytocin / pharmacology*
  • Pilot Projects


  • Oxytocin