Schinzel-Giedion syndrome with sacrococcygeal teratoma

J Pediatr Hematol Oncol. 2003 Jul;25(7):558-61. doi: 10.1097/00043426-200307000-00012.


A case of Schinzel-Giedion syndrome, a rare malformation syndrome, is described. In addition to the classic features of the syndrome, the patient had a malignant sacrococcygeal teratoma and agenesis of the corpus callosum. So far, this patient is the fifth case with a sacrococcygeal tumor and the eighth with anomalies of the corpus callosum. According to this occurrence of uncommon tumors, risk of malignancy could be a component of Schinzel-Giedion syndrome.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / diagnosis*
  • Abnormalities, Multiple / pathology
  • Endodermal Sinus Tumor / pathology*
  • Endodermal Sinus Tumor / surgery
  • Fatal Outcome
  • Female
  • Humans
  • Infant
  • Male
  • Sacrococcygeal Region*
  • Teratoma / diagnosis*
  • Teratoma / pathology
  • Teratoma / surgery
  • alpha-Fetoproteins / analysis


  • alpha-Fetoproteins