Bone involvement and abcess formation by neutrophil-rich CD30+ anaplastic large-cell lymphoma mimicking skeletal infection in an AIDS patient

J Infect. 2003 Jul;47(1):73-6. doi: 10.1016/s0163-4453(03)00005-7.

Abstract

Neutrophil-rich CD30+ anaplastic large-cell lymphoma (ALCL) is a rare pathological entity without distinct clinical behavior. Twelve cases of neutrophil-rich CD30+ anaplastic large-cell lymphoma (ALCL) have been reported, three of them were HIV-infected patients. All these reports stressed the presence of neutrophil infiltration as a new morphologic feature of CD30+ ALCL. Only one case of cutaneous involvement presented with microabscess formation. We describe a case of neutrophil-rich CD30+ ALCL in an AIDS patient with a clinical picture determined by the massive neutrophil infiltration of the tumor without necrosis nor local infection, but with the formation of abscesses.

Publication types

  • Case Reports

MeSH terms

  • Abscess / complications*
  • Adult
  • Diagnosis, Differential
  • Fatal Outcome
  • Humans
  • Ilium
  • Ki-1 Antigen / analysis*
  • Lymphoma, AIDS-Related / complications
  • Lymphoma, Large B-Cell, Diffuse / complications
  • Lymphoma, Large B-Cell, Diffuse / pathology*
  • Male
  • Neutrophils / pathology*

Substances

  • Ki-1 Antigen