Activation and signaling of the Abl tyrosine kinase: bidirectional link with phosphoinositide signaling

Cell Cycle. 2003 Jul-Aug;2(4):273-4.

Authors

Rina Plattner¹, Ann Marie Pendergast

Affiliation

¹ Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

PMID: 12851468

No abstract available

Publication types

Review

MeSH terms

Animals
Cell Division / physiology
Cell Movement / physiology
Enzyme Activation / physiology
Epidermal Growth Factor / metabolism
Phosphatidylinositol 4,5-Diphosphate / metabolism*
Phospholipase C gamma
Phosphorylation
Platelet-Derived Growth Factor / metabolism*
Protein Isoforms / metabolism
Protein Structure, Tertiary
Protein-Tyrosine Kinases / metabolism
Proto-Oncogene Proteins c-abl / metabolism*
Signal Transduction
Type C Phospholipases / metabolism*
src-Family Kinases / metabolism

Substances

Phosphatidylinositol 4,5-Diphosphate
Platelet-Derived Growth Factor
Protein Isoforms
Epidermal Growth Factor
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-abl
src-Family Kinases
Type C Phospholipases
Phospholipase C gamma